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A new treatment option for alcohol dependence: Reduced consumption rather...

A potential new treatment for alcoholism called nalmefene is effective and safe for reducing alcohol consumption in alcohol dependent individuals, says a new study published this week in Biological...

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NAFLD increases the risk of early atherosclerotic lesions

A study presented today at the International Liver Congress 2013 – which evaluated the relationship between non-alcoholic fatty liver disease (NAFLD), early predictors of atherosclerosis and the...

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Causal relationship between adiposity and heart failure, and elevated liver...

New evidence supports a causal relationship between adiposity and heart failure, and between adiposity and increased liver enzymes, according to a study published this week in PLOS Medicine. The study,...

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Study reveals link between oil spill exposure and hematologic and hepatic...

A new study reports that workers exposed to crude oil and dispersants used during the Gulf oil spill cleanup display significantly altered blood profiles, liver enzymes, and somatic symptoms compared...

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Coffee consumption reduces risk of liver cancer

Coffee consumption reduces risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, by about 40 percent, according to an up-to-date meta-analysis published in Clinical...

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Coffee and cigarettes may protect against liver disease, study says

Coffee and cigarette smoking may protect against the rare liver disease Primary Sclerosing Cholangitis (PSC), study shows.

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Impavido approved to treat tropical parasitic disease

(HealthDay)—Impavido (miltefosine) has been approved by the U.S. Food and Drug Administration to treat adults with leishmaniasis, a tropical disease caused by a parasite that's transmitted by the bites...

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Research questions liver disease prevalence in IBD

Do inflammatory bowel disease (IBD) patients have a higher prevalence of clinically significant liver disease?

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Study links coffee to lower liver cancer risk

(HealthDay)—Researchers say they've discovered yet another reason to love coffee: A new study suggests that people who drink at least a cup a day have a lower risk of liver cancer compared to those who...

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Zydelig approved for three types of blood cancer

(HealthDay)—Zydelig (idelalisib) has been approved by the U.S. Food and Drug Administration to treat relapsed forms of blood cancer, including chronic lymphocytic leukemia (CLL), follicular B-cell...

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Discovery may lead to new treatments for jaundice

Helping to protect newborns and older patients against more severe effects of jaundice is the hope of University of Guelph researchers, who have shown how a liver enzyme protects cells from damage...

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Genetic 'off switch' linked to increased risk factors for heart disease

Risk of heart and blood vessel disease may increase when a particular gene is switched off, according to preliminary research presented at the American Heart Association's Emerging Science Series Webinar.

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Researchers use RNAi to silence genes that cause transthyretin amyloidosis

(Medical Xpress)—An international team of researchers has discovered a way to silence the genes that cause transthyretin amyloidosis—a fatal genetic disease. In their paper published in the New England...

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Alcohol-breakdown molecule may play a role in breast cancer development

(Medical Xpress)—New research looking at the biological process involved in breast cancer development has strengthened the argument for a potential link between alcohol consumption and the disease.

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Elevated liver enzyme levels linked to higher gestational diabetes risk

Women with high levels of a common liver enzyme measured prior to pregnancy were twice as likely to subsequently develop gestational diabetes than those with the lowest levels, according to a Kaiser...

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Lean patients with fatty liver disease have higher mortality rate

Despite being of a healthier weight, lean patients with nonalcoholic fatty liver disease (NAFLD) have a higher overall mortality rate than patients with NAFLD who are overweight or obese, according to...

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Scientists discover mechanism for air pollution-induced liver disease

A research team led by Kezhong Zhang, Ph.D., at the Wayne State University School of Medicine's Center for Molecular Medicine and Genetics, has discovered that exposure to air pollution has a direct...

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Elevated liver enzymes common in severe anorexia nervosa

(HealthDay)—For adults with severe anorexia nervosa (AN), elevated liver enzymes are relatively common and are associated with lower body mass index (BMI) and hypoglycemia, according to research...

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How your genes influence what medicines are right for you

You have a headache. Do you reach for Tylenol or Advil? Most people have a preference because they have learned over time that one works better than the other at relieving their pain. This type of...

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Eating chocolate each day could reduce heart disease and diabetes risk

A new study published in the British Journal of Nutrition appears to back up the adage that a little of what you fancy does you good.

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Even light drinkers should watch for fatty liver disease

People who have reduced enzyme activity to breakdown active aldehyde, i.e., those who become easily inebriated, are more likely to develop fatty liver disease even if they do not drink alcohol. This...

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New tool to identify persons with nonalcoholic fatty liver disease

Researchers have developed a diagnostic model that is highly predictive of nonalcoholic fatty liver disease (NAFLD). Referred to as the Framingham Steatosis Index (FSI), this novel model may become a...

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Study identifies potential new avenue for treating pompe disease

Researchers at Duke Health have identified a potential new avenue for treating Pompe disease, a rare condition caused by the build-up of glycogen, a storage form of sugar, in cardiac and skeletal...

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Unexpected activity of two enzymes helps explain why liver cancer drugs fail

Some cancers are caused by loss of enzymes that should keep cell growth in check. On the flip side, some are caused by over-activation of enzymes that enhance cell growth. Yet drugs that inhibit the...

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Too many patients get liver tests they don't need, which can raise fears and...

It can start with the quick check of a box. A doctor orders a range of blood tests all at once, hoping to figure out what's causing a patient to show signs of liver damage. It sounds harmless enough -...

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Fatty liver diagnosis improved with magnetic resonance

Taking tissue samples from the liver to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation. This is the conclusion of a new study from Linköping...

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Intestinal fungi worsen alcoholic liver disease

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse. Yet apart from alcohol abstinence, there are no specific treatments to...

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Researchers see exosomes as way to make 'personalized medicine' easier and...

Today, doctors can tailor a drug therapy to your unique genetic profile, giving you the full benefits of a drug while reducing unwanted side effects—all in harmony with the blueprints of your biology.

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Survival feasible post acute liver failure secondary to amiodarone

(HealthDay)—In a report published online July 16 in the Journal of Clinical Pharmacy and Therapeutics, a case of survival after acute liver failure secondary to amiodarone administration is described.

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New regulator of liver metabolism discovered

Researchers from Charité - Universitätsmedizin Berlin have identified an enzyme that has a major effect on glucose utilization in liver cells. The enzyme, retinol saturase, helps these cells adapt to...

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